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Focus & Cognition

Semax

Nootropic peptide for focus and clarity · 400 mcg/day · 2–4 weeks

ACTH(4-10) analog · heptapeptide

A short neuropeptide known for focus, drive and mental clarity — the closest thing to a 'motivation' peptide, used in medicine in Russia for decades.

€29.9930 mg · LyophilizedIn stock

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Purity 99%+ HPLC

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Documentation CoA included

For laboratory and in vitro research use only. Not for human or veterinary use, and not for use in diagnostic procedures.

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ClassSynthetic heptapeptide

Half-lifeMinutes (effects last hours)

Typical routeNasal / SubQ

Cycle2–4 weeks

CategoryFocus & Cognition

Price€29.99

🧾 View Certificate of Analysis

About Semax

Semax is a synthetic heptapeptide developed as an analog of the ACTH(4-10) fragment, with a proline-glycine-proline extension that improves its stability. As a small, stable neuropeptide, it is widely used in neuroscience research model systems.

PX1 Labs supplies Semax as a 30 mg lyophilized powder verified at 99%+ identity purity by HPLC, with identity confirmed by mass spectrometry. A lot-specific Certificate of Analysis is included with every order.

What it's known for

Semax is best known for focus and cognition. Here is what it is most associated with. (Supplied for laboratory research use only; not approved as a medicine outside its Russian medical use.)

Focus & memory

Best known as a focus, memory and mental-clarity topic.

Brain support

Associated with brain protective factors such as BDNF.

Stress resilience

A popular stress-adaptation topic.

What research shows

Most human studies are from Russia; large Western trials are limited.

Semax explainers

Curated clips from across social media.

Swipe for more clips →

How it works

Semax is a short peptide derived from a fragment of the body's own ACTH hormone, but without the hormonal action. It is associated with signalling of brain protective factors (such as BDNF) — hence its reputation as a focus, memory and stress-resilience topic.

In Russia, Semax has been used in medicine for decades (e.g. in stroke and cognitive-support contexts), but it is not an approved medicine elsewhere.

What the evidence shows

Most human studies come from Russia and are smaller or use different methodology by Western standards; large Western clinical trials are lacking. An interesting but, outside Russia, unconfirmed topic.

An educational summary, not a treatment claim or medical advice.

Side effects & safety

Reference information — not medical adviceSummarised from public research literature. PX1 Labs products are supplied for laboratory research use only; not for human or veterinary use.

Commonly reported

Nasal irritation (intranasal use)
Mild headache
Transient changes in alertness or sleep

Cautions & contraindications

Most clinical use/data is from Russia; limited Western trials
Interactions with stimulant or psychiatric medication are not well characterised
Avoid in pregnancy/breastfeeding

Dosage chart (reference only)

Commonly cited ranges — not a recommendationBeginner / standard / advanced figures collected from public, widely available community references. Provided for reference and comparison only — not a dosing instruction or medical advice. Supplied for laboratory research use only.

Beginner	Standard	Advanced
200 mcg/day	400 mcg/day	600 mcg/day

Frequency	1–2× daily
Timing	Morning
Cycle length	2–4 weeks
Typical route	Nasal / SubQ

Convert any dose to a syringe draw →

Reference protocols

Reference only — not a recommendationThe figures below are commonly cited in public and community references. They are provided for reference and comparison only — not a dosing instruction, recommendation, or medical advice. PX1 Labs products are supplied for laboratory research use only; not for human or veterinary use.

Context	Commonly cited amount	Frequency
Injectable	200–600 mcg	1× daily
Nasal spray	common alternative	—

Reconstitution example: e.g. 30 mg + 3 mL → 10 mg/mL; 300 mcg = 0.03 mL. Many use a nasal spray instead.

Usually short courses (weeks), e.g. during focus or high-stress periods.

Work out your own draw in the calculator →

What researchers commonly report — by week

Commonly reported, not guaranteedThese timelines summarise what self-experimenters and widely available community sources describe. Individual results vary widely, many notice nothing on this schedule, and these are not promised outcomes. Reference information only — not medical advice. PX1 Labs products are supplied for laboratory research use only.

Day 1

Often felt the same day — focus, verbal fluency and drive (short-acting).

Week 1–2

Consistent daily focus and motivation with regular use.

Ongoing

Used as needed; effects described as acute, not cumulative.

Specifications

Every PX1 Labs lot is independently verified before dispatch. The figures below describe the product class; exact lot-specific results are documented on the Certificate of Analysis included with your order.

Compound class	Synthetic heptapeptide
CAS number	80714-61-0
Molecular formula	C₃₇H₅₁N₉O₁₀S
Molecular weight	813.9 g/mol
Identity purity	99%+ (HPLC)
Identity confirmation	Mass spectrometry
Presentation	30 mg lyophilized powder
Physical form	Sterile-filtered, freeze-dried
Storage	2-8°C; -20°C long term
Documentation	Lot-specific Certificate of Analysis

Documentation & quality

Semax passes the same five-stage PX1 quality process applied to every product: HPLC potency analysis, mass-spectrometry identity and purity confirmation, pH and stability validation, sterility and endotoxin (LAL) testing, and QC batch-consistency verification.

A lot-specific Certificate of Analysis ships with every order. The lot number printed on your vial matches the lot ID on the document, so the material on your bench can always be checked against the data on file.

References & research

Selected peer-reviewed literature on Semax (via PubMed), provided for educational context. A reference does not imply a clinical claim for PX1 Labs products.

Semax — questions

What is Semax derived from?

It is a synthetic analog of the ACTH(4-10) peptide fragment, modified for stability. Researchers should confirm the exact sequence against the Certificate of Analysis.

What size is the vial?

Each PX1 Semax vial contains 30 mg of lyophilized peptide, with a lot-specific Certificate of Analysis confirming 99%+ identity purity.

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Semax

About Semax

What it's known for

Focus & memory

Brain support

Stress resilience

What research shows

Semax explainers

Commonly reported

Cautions & contraindications

Specifications

Documentation & quality

References & research

Semax — questions

Often paired with

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BPC-157

MOTS-c

Retatrutide

Documented peptides, on your bench tomorrow.