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Metabolic & Longevity

MOTS-c

Mitochondrial peptide for metabolism and endurance · 10 mg 3×/wk · 4–8 weeks

Mitochondrial-derived peptide · 16 amino acids

A mitochondrial peptide encoded in mitochondrial DNA — known for metabolism, insulin sensitivity and an 'exercise-mimetic' reputation.

€39.9910 mg · LyophilizedIn stock

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Purity 99%+ HPLC

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Documentation CoA included

For laboratory and in vitro research use only. Not for human or veterinary use, and not for use in diagnostic procedures.

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ClassMitochondrial-derived peptide

Half-lifeHours

Typical routeSubQ

Cycle4–8 weeks

CategoryMetabolic & Longevity

Price€39.99

🧾 View Certificate of Analysis

About MOTS-c

MOTS-c is a mitochondrial-derived peptide of sixteen amino acids encoded within the 12S rRNA region of the mitochondrial genome. As one of a small family of peptides originating from mitochondrial DNA, it is a focus of research into mitochondrial-to-nuclear signaling and metabolic regulation.

PX1 Labs supplies MOTS-c as a 10 mg lyophilized powder verified at 99%+ identity purity by HPLC, with identity confirmed by mass spectrometry. A lot-specific Certificate of Analysis is included with every order.

What it's known for

MOTS-c is best known for metabolism and energy. Here is what it is most associated with. (Supplied for laboratory research use only.)

Metabolism

Associated with metabolic regulation and energy balance.

Insulin sensitivity

Studied for glucose handling and insulin response.

Exercise

Has an 'exercise-mimetic' reputation in the metabolic space.

What research shows

Mainly animal and cell data so far; human research is at an early stage.

MOTS-c explainers

Curated clips from across social media.

Swipe for more clips →

How it works

MOTS-c is a so-called mitochondrial peptide — a short sequence whose 'instructions' come from the mitochondria's own DNA. In lab work it is associated with metabolic regulation, insulin sensitivity and cellular energy balance, especially in the context of exercise.

What the evidence shows

Evidence comes mainly from animal and cell studies; human research is at an early stage. A promising but early topic — not an approved medicine.

An educational summary, not a treatment claim or medical advice.

Side effects & safety

Reference information — not medical adviceSummarised from public research literature. PX1 Labs products are supplied for laboratory research use only; not for human or veterinary use.

Commonly reported

Injection-site irritation
Transient fatigue or light-headedness
Mild GI upset

Cautions & contraindications

Human data is very limited (early research)
May influence blood glucose / insulin sensitivity
Avoid in pregnancy/breastfeeding

Dosage chart (reference only)

Commonly cited ranges — not a recommendationBeginner / standard / advanced figures collected from public, widely available community references. Provided for reference and comparison only — not a dosing instruction or medical advice. Supplied for laboratory research use only.

Beginner	Standard	Advanced
5 mg 3×/wk	10 mg 3×/wk	10 mg 5×/wk

Frequency	3–5×/week
Timing	Morning
Cycle length	4–8 weeks
Typical route	SubQ

Convert any dose to a syringe draw →

Reference protocols

Reference only — not a recommendationThe figures below are commonly cited in public and community references. They are provided for reference and comparison only — not a dosing instruction, recommendation, or medical advice. PX1 Labs products are supplied for laboratory research use only; not for human or veterinary use.

Context	Commonly cited amount	Frequency
Commonly cited	5–10 mg per week	split into 2–3 amounts

Reconstitution example: e.g. 10 mg + 2 mL → 5 mg/mL; 5 mg = 1 mL.

Often 4–8-week courses, frequently tied to a training block.

Work out your own draw in the calculator →

What researchers commonly report — by week

Commonly reported, not guaranteedThese timelines summarise what self-experimenters and widely available community sources describe. Individual results vary widely, many notice nothing on this schedule, and these are not promised outcomes. Reference information only — not medical advice. PX1 Labs products are supplied for laboratory research use only.

Week 1–2

A bump in workout energy and endurance commonly reported.

Week 3–4

Steadier energy and metabolic ‘feel’ noted.

Week 6+

Endurance and body-composition changes cited alongside training.

Specifications

Every PX1 Labs lot is independently verified before dispatch. The figures below describe the product class; exact lot-specific results are documented on the Certificate of Analysis included with your order.

Compound class	Mitochondrial-derived peptide
CAS number	1627580-64-6
Molecular formula	C₁₀₁H₁₅₂N₂₈O₂₂S₂
Molecular weight	≈ 2174.6 g/mol
Identity purity	99%+ (HPLC)
Identity confirmation	Mass spectrometry
Presentation	10 mg lyophilized powder
Physical form	Sterile-filtered, freeze-dried
Storage	2-8°C; -20°C long term
Documentation	Lot-specific Certificate of Analysis

Documentation & quality

MOTS-c passes the same five-stage PX1 quality process applied to every product: HPLC potency analysis, mass-spectrometry identity and purity confirmation, pH and stability validation, sterility and endotoxin (LAL) testing, and QC batch-consistency verification.

A lot-specific Certificate of Analysis ships with every order. The lot number printed on your vial matches the lot ID on the document, so the material on your bench can always be checked against the data on file.

References & research

Selected peer-reviewed literature on MOTS-c (via PubMed), provided for educational context. A reference does not imply a clinical claim for PX1 Labs products.

MOTS-c — questions

What makes MOTS-c unusual?

It is encoded within mitochondrial DNA rather than the nuclear genome — one of a small class of mitochondrial-derived peptides, which makes it a distinctive subject for metabolic research.

How is MOTS-c supplied?

As a 10 mg lyophilized powder in a sealed vial, with a lot-specific Certificate of Analysis documenting 99%+ identity purity.

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MOTS-c

About MOTS-c

What it's known for

Metabolism

Insulin sensitivity

Exercise

What research shows

MOTS-c explainers

Commonly reported

Cautions & contraindications

Specifications

Documentation & quality

References & research

MOTS-c — questions

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CJC-1295 & Ipamorelin

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Documented peptides, on your bench tomorrow.